By Stanley T. Crooke,Archie W. Prestayko
Part I is a normal assessment of anti-cancer medications as regards their motion mechanisms, pharmacokinetics, pharmacology, identified toxicities, and scientific software. those medicinal drugs comprise alkylating brokers corresponding to mitomycin C and nitrosoureas; plant alkaloids corresponding to maytansine; antibiotics resembling anthracyclines; platinum-containing complexes; antimetabolites; and hormones. half II examines the molecular pharmacology of a few significant drug periods, specifically, bleomycin and anthracycline. The textual content additionally discusses the chemistry, mechanism, and any structure-activity relationships present in those drug sessions. half III discusses intimately the medical pharmacology of a few antitumor medications, for instance, cisplatin and nitrosoureas. The textual content comprises the medical functions, biochemistry, metabolism, and using mathematical types in analyzing or describing ensuing info.
The e-book is useful for pharmacologists, molecular biologists, and scientists all in favour of cancer-research.
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Antineoplastic Agents: Antineoplastic Agents v. 3 by Stanley T. Crooke,Archie W. Prestayko